Cannabidiol found by researchers in common Brazilian plant

Researchers from the Federal University of Rio de Janeiro (UFRJ) have identified cannabidiol (CBD) in the fruits and flowers of the Trema micrantha Blume, a native Brazilian plant. Unlike Cannabis sativa, In Brazil, this species does not contain tetrahydrocannabinol (THC), the psychoactive compound responsible for marijuana's hallucinogenic effects. This discovery could therefore facilitate the production of CBD-based medicines in Brazil, without the legal restrictions associated with cannabis cultivation.

Why Trema micrantha is it a promising alternative?

• No THC: The plant has no THC, eliminating legal and psychoactive concerns associated with cannabis.
• Wide distribution: Found in various regions of Brazil, such as Rio de Janeiro, Minas Gerais and Goiás, it is easy to access and cultivate.
• Traditional useUsed in reforestation and in folk medicine to treat skin rashes.
• Rapid growthIdeal for large-scale cultivation due to its rapid growth.

Impact on the medicinal use of cannabidiol

The discovery of Trema micrantha as a source of CBD could increase access to treatments for various health conditions, for example:

• Epilepsy
• Psychiatric disorders
• Neurodegenerative diseases
• Chronic pain
• Anxiety

What's more, because they don't contain THC, medicines derived from this plant can be more easily regulated and distributed in the public health system.

Next steps in the research

The UFRJ team, led by biologist Rodrigo Soares Moura Neto, is focused on:

• Developing effective methods for extracting CBD from Trema micrantha.
• Carry out in vitro tests to compare the efficacy of extracted CBD with that of Cannabis sativa.
• To seek partnerships for industrial-scale production in order to meet the growing demand for cannabidiol-based treatments.

The identification of cannabidiol in Trema micrantha represents a significant advance in cannabidiol research in Brazil. In addition, this native plant offers a viable and legal alternative for the production of CBD, boosting access to medicinal treatments and driving the development of new drugs in the country.

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